Despite extensive research efforts, cancer continues to stand as one of the leading causes of death on a global scale.To gain profound insights into the intricate mechanisms underlying cancer onset and progression, it is imperative to possess methodologies that allow the study of cancer cells at the single-cell level, focusing on critical parameter
The application of metabolomics in phytochemical analysis is an innovative strategy for targeting active compounds from a complex plant extract.Species of the Asteraceae custom congratulations banner family are well-known to exhibit potent anti-inflammatory (AI) activity.Dual inhibition of the enzymes COX-1 and 5-LOX is essential for the treatment
Abstract Background We aimed to identify healthcare needs, expectations, utilization, and the experienced treatment effects in a population of Dutch patients with hereditary spastic paraplegia (HSP).Methods We distributed an online questionnaire among 194 adult persons with HSP in the Netherlands, of which 166 returned a fully completed version.Aft
In their click here seminal works on squid giant axons, Hodgkin and Huxley approximated the membrane leak current as Ohmic, i.e.linear, since in their preparation, sub-threshold current rectification due to the influence of ionic concentration is negligible.Most studies on mammalian neurons have made the same, largely untested, assumption.Here we s
The Cerrado in the Central Brazil is currently one of the most threatened ecosystems in the world.As a result, the aquatic habitats in this biome also undergo great impacts.Alterations related to land-use change increase sediment loadings in rivers, streams and lakes, resulting in sedimentation and decrease in water transparency.Water transparency